Work

Optimized Used Of Solvents In Active Pharmaceutical Ingredients Production by Angelini Eternal Case Study 2

Year: 2026

Type: article

Abstract: As part of the Horizon Europe ETERNAL project, Angelini Pharma has investigated the possibility to upgrade in capability of the distillation used to achieve a challenging mixed solvent separation and recovery duty associated with a current commercial process, while studying the opportunity of substituting green, bio-based solvent alternatives for conventional solvents in Active Pharmaceutical Ingredients (APIs) manufacture whilst work continues. The main objective was to capture impurities and unreacted formulation components generated during the production of the chemical, as well as those present in the waste products.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.22208376

Authors: Iacoangeli, Tommaso, Taffuri, Andrea

Institution: Angelini Pharma (Italy)

Language: English

Topic: Process Optimization and Integration

Subfield: Control and Systems Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Responsible consumption and production

Open Access status: green

Funder: European Commission