Year: 2026
Type: preprint
Study design: Case Report
Abstract: A 47 years old woman with seven years of pruritus and abdominal distension was diagnosed with primary biliary cirrhosis with chronic liver disease. A month after she developed bruises/petechie on hands and legs. The Platelet count abruptly increased with steroid therapy. She has multiple relapses of thrombocytopenia to a very lesser counts i.e. 6000.The association between these two conditions is rare and only few cases has been reported previously in Japan. Conclusion : This case supports a rare autoimmune association between primary biliary cholangitis and idiopathic thrombocytopenic purpura after exclusion of viral, drug-related, hyper splenic, and marrow-related causes of thrombocytopenia.
Source: Research Square
Language: English
Topic: Liver Diseases and Immunity
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7204781027