Comparison of efficacy and safety between bilateral single-session PCNL and bilateral staged PCNL in preschool children
Year: 2026
Type: article
Study design: Observational Study
Abstract: Objective: Bilateral kidney stones in preschool children are challenging to manage, and the optimal surgical strategy remains unclear.This study aimed to compare the efficacy and safety of bilateral single-session percutaneous nephrolithotomy (PCNL) and bilateral staged PCNL in preschool children with bilateral kidney stones.Methods: We retrospectively reviewed preschool children aged <7 years with bilateral kidney stones who underwent PCNL at our two centers between June 2014 and June 2025.Patients were divided into a bilateral staged PCNL group and a bilateral single-session PCNL group.Perioperative outcomes, stone-free rate (SFR), and complication rate (CR) were compared, and logistic regression analyses were performed to identify factors associated with SFR and CR.Results: No significant difference in SFR (per renal unit) was observed between the bilateral single-session PCNL group and the bilateral staged PCNL group (87.18% vs. 72.92%,p = 0.232).CR (per person) was also comparable between the two groups (43.59% vs. 33.33%,p = 0.419), and all recorded complications were low-grade and manageable, corresponding to Clavien-Dindo Grades I-II.Multivariable logistic regression analysis showed that bilateral single-session PCNL was independently associated with a higher SFR compared with bilateral staged PCNL (odds ratio [OR]: 11.75; 95% confidence interval [CI]: 1.62-85.15;p = 0.015).Tract size >4.8Fr was also independently associated with a higher SFR (OR: 5.73; 95% CI: 1.01-32.61;p = 0.049).No evaluated variable was significantly associated with CR.Conclusion: Bilateral single-session PCNL is an effective therapeutic strategy for the management of preschool children with bilateral kidney stones, providing stonefree outcomes and complication rates comparable to those of bilateral staged PCNL.
Source: Canadian Journal of Urology
Language: English
Subfield: Urology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7204800217