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An IRAK1-snRNA axis activates ATM to promote accurate repair within transcriptionally active chromatin

Year: 2026

Type: article

Source: Molecular Cell

DOI: 10.1016/j.molcel.2026.08.006

Authors: Chen Nie, Wanchang Liu, Lei Zhang, Sai Ge, Mingyang Ma, Jundi Wang, Zhanzhan Xu, Yingyu Qin, Xiao Albert Zhou, Yang Liu, Weibin Wang, Jiadong Wang

Institutions: Peking University, State Key Laboratory of Molecular Oncology, Guizhou Provincial People's Hospital, Peking University Cancer Hospital, Inner Mongolia Medical University, Beijing Tsinghua Chang Gung Hospital, Tsinghua University, Peking University First Hospital

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Natural Science Foundation of Inner Mongolia, China National Funds for Distinguished Young Scientists, Young Scientists Fund

OpenAlex ID: W7204803706

FWCI:

Cites: 89

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Related to: 10