Work

Sulfoximines as Secondary Sulfonamide Isosteres: Paradoxical Impact on Solubility and Plasma Protein Binding

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c01919

Authors: Sandra M. King, Ming Qian, Will Sii Hong Lau, Cristian Draghici, Tanzina Fazal, Pankaj Jain, Jeff Jin, Richard A. Lewis, Donglei Liu, Larry Miller, Wosenu Mergo, Jacob O’Leary, Keith Pfister, Maria Phan, Suzanne M. Skolnik, Xilin Zhou, Michael D. Shultz

Institution: Novartis (Switzerland)

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Drug Discovery

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: closed

OpenAlex ID: W7204854535

FWCI: 3.163

Cites: 92

Cited by: 2

Related to: 10