Year: 2026
Type: article
Abstract: Central foveal bouquet anomalies (CFBA) represent spectrum of tractional and nontractional changes in the fovea, emerging primarily in epiretinal membrane and cystoid macular edema. In recent years, due to optical coherence tomography of the retina, interest among clinicians in these changes has increased significantly due to their impact on central vision and the prognosis of surgical treatment of vitreomacular interface diseases. A search of publications was performed in the eLIBRARY.RU, PubMed, Google Scholar, and UpToDate databases using the terms «central foveal bouquet anomalies» in English and Russian languages. It was confirmed that the pathogenesis of CFBA is associated with mechanical stress on the foveola transmitted through Müller cells and can be realized as traction tension in epiretinal membranes or vertical stretching of the retina in cystoid macular edema. Three sequential stages of CFBA (cotton ball sign, foveal detachment and acquired vitelliform lesion) are described. They accompanied by progressive loss of visual acuity and increasing damage to the ellipsoid zone. Optical coherence tomography of the retina plays a key role in the detailed visualization of these stages. Detection of CFBA in patients with epiretinal membrane and cystoid macular edema has important prognostic value, allowing for a more informed approach to the selection of treatment strategies and assessment of the expected functional outcomes of vitreoretinal surgery. Keywords: central foveal bouquet anomalies retinal diseases, vitreomacular interface, vitreomacular traction, epiretinal membrane, cystoid macular edema, optical coherence tomography, cotton ball sign, acquired vitelliform lesion
Source: POINT OF VIEW EAST – WEST
Authors: R.S. Zhazybaev, A.L. Zhirov
Language: English
Topic: Retinal and Macular Surgery
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7204930604