The hypotensive effect of simultaneous combined laser treatment of ocular hypertension and primary openangle glaucoma associated with pigment dispersion syndrome
Year: 2026
Type: article
Study design: Clinical Trial
Abstract: Purpose. To evaluate the hypotensive effect of simultaneous combined laser treatment of ocular hypertension and primary openangle glaucoma (POAG) associated with pigment dispersion syndrome (PDS). Material and methods. A prospective analysis of the hypotensive effect was performed in 47 patients (47 eyes) with ocular hypertension against the background of SD, initial and developed stages of POAG. The patients were divided into two groups. Group 1 (the study group) included 22 patients (22 eyes) who underwent simultaneous combined laser treatment. Group 2 (the control group) included 25 patients (25 eyes) who underwent only SLT. The differences between the groups based on gender and age of the patients were statistically insignificant (p>0.05). The follow-up period was 12 months. The main criteria for evaluating the treatment outcomes were the success and failure rates based on the target IOP values. Results. The absolute success in IOP compensat after combined laser technology was 98% after 3 months, and the absolute success in IOP compensation remained high at 95% after 6 months. The absolute success in IOP compensation after SLT was not observed after 3 and 6 months, and only relative success was achieved after 3 months in 100% of cases and after 6 months in 91% of cases. 12 months after one-stage combined laser technology, the rate of absolute success in compensation of IOP was 89%, only in 11% of cases, SRT or topical hypotensive therapy was required. In patients of the control group, absolute success in compensation of IOP was not traced, only relative success was observed in 21% of cases, in 79% of this group additional treatment was required. Conclusion. The proposed technology of simultaneous combined laser treatment of ocular hypertension and PG associated with SPD showed a pronounced and stable hypotensive effect throughout the entire follow-up period. Keywords: pigment dispersion syndrome, primary open-angle glaucoma, selective laser trabeculoplasty, laser surgery
Authors: K.V. Obodova, N.V. Strenev
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7204989760