Supplementary Figure S7 from A Novel CDK12 Inhibitor Induces Homologous Recombination Deficiency to Enhance PARP Inhibitor Efficacy in Uterine Serous Carcinoma
Year: 2026
Type: supplementary-materials
Abstract: Supplementary Figure S7 shows longitudinal body weight monitoring in mice bearing ARK2 xenografts treated with vehicle, CTX-439, olaparib, or their combination, demonstrating no significant treatment-related weight loss during the dosing period.
Authors: Shunsuke Kawahara, Mana Taki, Junzo Hamanishi, Shunsuke Ebara, Ryusuke Murakami, Kohei Hamada, Koichi Watanabe, Yuko Hosoe, Yuka Mise, Shiro Takamatsu, Taito Miyamoto, Rin Mizuno, Koji Yamanoi, Ken Yamaguchi, Hiroko Yamakawa, Nobuyuki Kakiuchi, Tsukasa Baba, Seishi Ogawa, Daisuke Morishita, Kosuke Yusa, Masaki Mandai
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7204993178