Dystonia 3×3: A Training Guideline for Beginners in Botulinum Neurotoxin Treatment of Cervical Dystonia
Year: 2026
Type: article
Abstract: Cervical dystonia (CD) is a hyperkinetic movement disorder characterized by involuntary muscle contractions leading to abnormal postures of the head and neck. The injection of botulinum neurotoxin type A (BoNT-A) into the muscles involved is the treatment of choice for CD. BoNT-A therapy of CD requires appropriate training, which has not been standardized in Germany. To address the key challenges in BoNT-A education, an expert panel developed a simplified step-by-step treatment guideline for beginners, adapted from the established Col-Cap-Concept ("Dystonia 3×3"). Based on expert consensus, recommendations were developed for the core clinical elements of BoNT-A treatment in CD-recognition of the movement pattern, identification of target muscles, development of an injection plan, ultrasound-guided injection, and dosing, taking into account the target audience of the guideline. As such, Dystonia 3×3 provides a user-friendly beginner's guidebook, enhancing accessibility and standardization of CD treatment training. Further research is required to evaluate its clinical efficacy and suitability for training.
Source: Toxins
Institutions: University Hospital Bonn, Technical University of Munich, Universitätsklinikum Aachen, RWTH Aachen University, Universitätsklinikum Würzburg, Parkinson-Klinik Ortenau, Saarland University, Vivantes Klinikum, Knappschaftskrankenhaus Recklinghausen, Düsseldorf University Hospital, Heinrich Heine University Düsseldorf, German Center for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Universitätsmedizin Rostock, Asklepios, Leipzig University
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,258
OpenAlex ID: W7204993385
