Work

Retrospective study of the impact of the retrograde autologous prime blood conservation method used in open heart surgery on postoperative hemogram and blood transfusion

Year: 2026

Type: article

Abstract: Cardiopulmonary bypass (CPB) is an extracorporeal circulation (ECC) system that temporarily takes over the heart and lung functions during open-heart surgery, providing oxygen support to the tissues.[1] In CPB applications, while the methods of oxygenator priming vary between centers, crystalloid solutions are widely preferred in adult patients.[2] Crystalloids used in CPB increase blood volume, leading to hemodilution and changes in the intravascular oncotic balance.[3] Hemodilution associated with CPB leads to a decrease in hematocrit (HCT) levels; it can cause significant complications such as renal dysfunction, prolonged intensive care unit (ICU) stay, and increased duration of mechanical ventilation.[4] Hemodilution that occurs during CPB leads to hematological changes, significantly increasing the need for transfusion.However, the use of blood products is associated with serious side effects such as immunological reactions, infectious complications, and transfusionrelated acute lung injury.All these factors are significant risk elements that increase morbidity and mortality rates.[5]

Source: Cardiovascular Surgery and Interventions

DOI: 10.4274/e-cvsi.2026.2026-5-4

Authors: Ayşegül Yılmaz, Mehmet Ali Yürük

Institution: Karadeniz Technical University

Language: English

Topic: Blood transfusion and management

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7204995361