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Enniatins and Beauvericin Emerging Mycotoxins Affect Pigs' Metabolome

Year: 2023

Type: conference-paper

Abstract: In addition to deoxynivalenol, fumonisins and zearalenone, Fusarium fungi produce other toxins such as beauvericin or enniatins, which are called “emerging” mycotoxins (EMs). Occurrence data and biological effects for EMs are still limited. Recently, feed ingredients were shown to contain 66% to 98% of beauvericin, enniatin B, aurofusarin or apicidin [1]. In vitro, data suggest that BEA and ENN induce cytotoxicity, oxidative stress and apoptosis. In vivo, while they do not induce apparent acute mycotoxicosis, no conclusion can be drawn on chronic exposure. To study the impact of EMs, we conducted a LC-MS based metabolomics study of plasma and liver of piglets (5 weeks) fed with a mixture of enniatins B, B1 and beauvericin during 14 days.

Source: HAL

Authors: Jamin, Emilien, Oules, Justin, Martin, Jean-François, Novak, Barbara, Schatzmayr, Dian, Oswald, Isabelle P., Puel, Olivier, Pinton, Philippe

Institutions: MetaboHUB, Biomin (Austria), Toxicologie Alimentaire

Language: English

Topic: Mycotoxins in Agriculture and Food

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDGs: Zero hunger, Good health and well-being

Open Access status: green

OpenAlex ID: W7205597215

FWCI:

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