Year: 2026
Type: article
Study design: Case Report
Abstract: Acetaminophen is widely used as a safe antipyretic and analgesic; however, acetaminophen-induced lung injury is rare. We report a case of drug-induced interstitial pneumonia in an 84-year-old man who developed bilateral ground-glass opacities on chest computed tomography after initiation of a combination therapy with tramadol and acetaminophen. Discontinuation of the medication led to rapid clinical and radiological improvement. Because a drug-induced lymphocyte stimulation test for acetaminophen was positive and there have been no reports of tramadol-induced pulmonary injury, acetaminophen was considered the causative agent. This case highlights the importance of considering acetaminophen as a potential cause of unexplained pneumonia.
DOI: 10.14999/0002000646
Institution: Kawanishi City Hospital
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7207791632