Year: 2008
Type: article
Study design: Case Report
Abstract: ：We herein report a patient with hepatoblastoma who was born at 29 weeks and one day of gestation with a birth weight of 507 g, thus presenting as an extremely low birth weight infant.The patient received oxygen for 320 days at the neonatal intensive care unit.His care continued at the outpatient clinic because of low body weight gain until he was thereafter found to have an abdominal tumor when he was 12 months old.The histology was poorly differentiated(fetal and embryonal)type hepatoblastoma, and the clinical stage was Ⅲ according to the Pre Treatment Extent of Disease System by the International Society of Pediatric Oncology.He received a liver transplant from his mother because chemotherapy was ineffective.He died 10 months after the transplantation because of a relapse of the tumor.The incidence of hepatoblastoma is higher among low birth weight children than those born with a normal birth weight.A lower birth weight correlates with a higher incidence of hepatoblastoma.The administration of oxygen, which is necessary for the low birth weight infants, is thought to be related to the occurrence of hepatoblastoma.As a result, low birth weight infants with a high risk of developing hepatoblastoma therefore need a careful follow up.Key words：Hepatoblastoma, Extremely low birth weight infant, Oxygen, Follow up
Institutions: Fukuoka University, Fukuoka Tokushukai Hospital
Language: Japanese
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7208036075