淋菌性尿道炎に対するpipemidic acidの臨床効果について
Year: 1985
Type: article
Study design: Clinical Trial
Abstract: Twenty cases of gonorrhoeal urethritis were orally treated with pipemidic acid (PPA). The results are as follows. The clinical effect of PPA was excellent in 9 cases and good in 6 cases, the efficacy rate being 75%. The usefulness of PPA was satisfactory in 12 cases (60%). No side effects were observed. The minimal inhibitory concentrations against 14 isolated Neisseria gonorrhoeal strains ranged from 0.78 to 3.13 micrograms/ml with a median value of 1.56 micrograms/ml. A beta-lactamase-producing strain was observed among the 14 strains and the case infected by this strain was successfully treated with PPA. These results indicate that PPA is a useful drug for the treatment of gonorrhoeal urethritis.
Authors: YASUMOTO, Ryoji, MORIKAWA, Yoji, HORII, Akinori, KAWAKITA, Junji, KOBAYAKAWA, Hitoshi, WADA, Seiji, SAKAMOTO, Wataru, OZAKI, Yukichi, NISHIJIMA, Takaaki
Institution: Osaka City University
Language: Japanese
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7208526236