Advancements in Natural Polysaccharides for Regulating Intestinal Flora to Improve Type 2 Diabetes Mellitus
Year: 2024
Type: article
Abstract: Natural polysaccharides can promote the proliferation of beneficial bacteria in the intestinal tract, inhibit pathogenic bacteria growth, and maintain intestinal flora diversity. They can also improve diseases caused by microbiota dysbiosis by regulating intestinal flora composition. Type 2 diabetes mellitus (T2DM) is a typical chronic metabolic disease, and its onset and progression are closely associated with dysbiosis of the intestinal flora. Natural polysaccharides can treat and alleviate diabetes by affecting the intestinal flora's species, quantity, abundance, and metabolic pathway. Treatment and intervention of T2DM by regulating intestinal flora have become directions in diabetes treatment. This study reviewed the natural polysaccharides that improve T2DM by regulating intestinal flora in recent years, including the relationship between intestinal flora and T2DM and the regulation and mechanism of natural polysaccharides on the intestinal tract of T2DM. This work guides the future utilization of natural polysaccharide resources and the management of T2DM.
Institutions: Youjiang Medical College for Nationalities, Mahsa University
Language: English
Topic: Gut microbiota and health
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W7208711527