Work

Selenoproteome dynamics in the gut microbiome across disease severity in ulcerative colitis

Year: 2025

Type: conference-paper

Abstract: Selenoproteins are a class of proteins with selenocysteine replaced instead of cystein residues. This modification greatly enhances nucleophilicity and redox activity properties and therefore play a critical role in oxidative stress. Selenium at or near the catalytic center enables these proteins to efficiently reduce reactive oxygen species (ROS) and restore oxidatively modified biomolecules. By acting as key antioxidant components, they promote cellular resilience during oxidative stress, such as that present in for example inflamed tissue.

Source: VBN Forskningsportal (Aalborg Universitet)

Authors: Hansen, Kristian Riis, Østergaard, Stine Karstenskov; id_orcid 0009-0001-1092-0826, Lund Nielsen, Jeppe; id_orcid 0000-0002-8747-6938

Language: English

Topic: Selenium in Biological Systems

Subfield: Nutrition and Dietetics

Field: Nursing

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7208800540

FWCI:

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