Work

Sustained multisite response to anifrolumab in refractory Chilblain lupus erythematosus

Year: 2026

Type: article

Abstract: hilblain lupus erythematosus (CHLE) is a rare variant of chronic cutaneous lupus erythematosus, closely associated with systemic lupus erythematosus (SLE) and other lupus-spectrum connective tissue diseases. It presents with cold-induced, pruritic or painful violaceous lesions on acral sites that may ulcerate, fissure, become hyperkeratotic, or form atrophic plaques.1

Source: JAAD Case Reports

DOI: 10.1016/j.jdcr.2026.08.051

Authors: Sarah John, Lisabeth V. Scalzi, Galen Foulke, Matthew Helm

Institutions: Pennsylvania State University, Penn State Health Children's Hospital, Penn State Milton S. Hershey Medical Center

Language: English

Topic: Systemic Lupus Erythematosus Research

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $750