A clinical study to assess the effectiveness of homoeopathic constitutional medicine in the management of peptic ulcer disease
Year: 2026
Type: article
Abstract: Background: Peptic Ulcer Disease (PUD) is characterized by ulceration of the gastric or duodenal mucosa. The major established causes include Helicobacter pylori infection and the use of aspirin or other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). These factors may act independently or synergistically in the development of peptic ulceration and ulcer complications [1-4]. Current management emphasizes identification and eradication of H. pylori, withdrawal or modification of ulcero-genic NSAID exposure where possible, and appropriate acid-suppressive therapy [3-5]. Homoeopathy is a system of individualized treatment in which medicine selection is based on the totality of symptoms and the individual characteristics of the patient. The present clinical study is designed to assess the effectiveness of constitutional homoeopathic treatment in patients diagnosed with peptic ulcer disease. Aim: To assess the effectiveness of homoeopathic constitutional medicine in the management of peptic ulcer disease. Objectives 1. To assess changes in the clinical symptoms of patients with peptic ulcer disease following individualized homoeopathic treatment. 2. To study the distribution of constitutional homoeopathic medicines prescribed in the selected patients. 3. To assess changes in the quality of life and symptom severity of patients during the study period. 4. To document any adverse events or treatment-related concerns during the study. Methods: A prospective clinical study will be conducted among patients diagnosed with peptic ulcer disease who satisfy predefined inclusion and exclusion criteria. Detailed homoeopathic case-taking will be performed, including presenting complaints, location, sensation, modalities, concomitant symptoms, mental and general characteristics, past history, family history, personal history and relevant physical findings. Individualized constitutional medicines will be selected according to the totality of symptoms and the principles of homoeopathic prescribing. Baseline assessment will be performed before treatment and repeated at predefined follow-up intervals. Clinical improvement will be evaluated using a predefined symptom/outcome scoring system. Appropriate conventional investigation and referral will be undertaken when clinically indicated, particularly in patients with alarm features or suspected complications. Results: The results has been reported after completion of the study using the actual number of enrolled participants, completed cases, demographic characteristics, baseline scores, follow-up scores, statistical tests and corresponding p-values. No numerical results has been inserted unless they are obtained from the actual patient dataset. Conclusion: The study is intended to provide prospective clinical data regarding the response of patients with peptic ulcer disease receiving individualized constitutional homoeopathic treatment. The findings should be interpreted cautiously and in the context of established evidence-based management of peptic ulcer disease. Homoeopathic treatment should not replace proven treatment for H. pylori, gastrointestinal bleeding, perforation, obstruction or other serious complications.
Author: Bharathkumar .
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7210272576