Impacto da vacinação contra o HPV na mortalidade por câncer do colo do útero no Brasil: uma análise epidemiológica
Year: 2026
Type: article
Study design: Observational Study
Abstract: Human papillomavirus (HPV) Human papillomavirus (HPV) infection is the most prevalent sexually transmitted infection worldwide and represents the main risk factor for the development of cervical cancer. HPV vaccination was introduced as a preventive strategy; however, its effectiveness in reducing mortality still requires detailed epidemiological evaluation. This observational, retrospective, and quantitative study used data from DATASUS (SIM and SI-PNI) via TabNet to analyze cervical cancer mortality (ICD-10: C53) and HPV vaccination coverage in pre-vaccine (2005–2014) and post-vaccine (2015–2023) periods, stratified by year, region, state, and age group. An increase in deaths was observed, from 50,023 to 58,506, with an average annual variation of 1.88% and 2.54%, respectively. The Southeast region concentrated the highest number of cases, followed by the Northeast, and the 50–59-year age group was the most affected. It is concluded that although vaccination represents a major preventive advance, its effectiveness depends on expanding vaccine coverage, strengthening screening programs, and reducing regional inequalities in access to healthcare.
Source: Amazônia Science & Health
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7212371893