Work

Two types of mutations (G275E and three-amino acid deletion) in the nicotinic acetylcholine receptor α6 subunit confer different levels of resistance to spinosad in Thrips tabaci (Thysanoptera: Thripidae)

Year: 2026

Type: article

Abstract: Populations of arrhenotokous and thelytokous Thrips tabaci (Thysanoptera: Thripidae) that have developed resistance to spinosad have been identified in fields in Japan.Resistance to spinosad was moderate in resistant strains of arrhenotokous, whereas it was high in those of thelytokous.Variant analysis of the target gene of spinosad, nicotinic acetylcholine receptor α6 subunit, revealed that a well-known G275E mutation was present in the moderately resistant arrhenotokous strain, whereas a three-amino acid deletion in the fourth transmembrane domain, which has not been previously reported in the thrip species, was identified in highly resistant thelytokous strains.The deletion site is highly similar to the previously reported three-amino acid deletion in the target gene of the diamondback moth, Plutella xylostella, which conferred high resistance to spinosad.These results indicate that two types of mutations identified in T. tabaci strains confer different levels of resistance to spinosad.

Source: Journal of Pesticide Science

DOI: 10.1584/jpestics.d26-027

Authors: Akiya Jouraku, Ibuki Hasegawa, Seigo Kuwazaki, Hiroyuki Iida, Misato Aizawa, Shoji Sonoda