EP838 - ECE_2208 - Cardiovascular risk factors in patients with newly diagnosed type 2 diabetes
Year: 2026
Type: conference-abstract
Abstract: Background Type 2 diabetes (T2D) is associated with an increased risk of cardiovascular disease (CVD) and CV mortality. Additionally, multiple modifiable risk factors (obesity, dyslipidemia, hypertension) can further increase the risk of a poor outcome. Hence early identification of CVD risk factors in patients with T2D is crucial for proactive management and primary prevention. Objectives Assessment of cardiovascular risk factors and stratification of CVD risk in patients with newly diagnosed T2D. Methods A retrospective study was conducted among newly diagnosed T2D patients attending the outpatient clinic. Anthropometric measurements (BMI, WHR), biochemical parameters (lipid panel, HbA1c) and past medical history were analyzed. Control group included patients matched by gender and age, without diabetes. The stratification of CVD risk was performed using SCORE2-Diabetes and SCORE2 in patients with T2D and controls respectively. Results 100 patients with T2D were enrolled (50F, 50M), median age 52 years [IQR 47-55]. Glycemic control was optimal with median HbA1c—7.1% [6.7-7.5]. Obesity was observed in 45% of T2D patients and 32% were overweight with BMI 30.6 [25.6-36.4] and WHR 0.95 [0.82-1.09]. Dyslipidemia was found in 61% of T2D patients with LDL—3.6 [2.97-4.1] mmol/L and triglycerides—1.76 [1.3-2.12] mmol/L that were significantly higher vs controls with LDL—2.7 [2.39-3.37] mmol/L and triglycerides—1.19 [0.93-1.49] mmol/L (P < .5). In addition to a higher level of HDL—1.3 [1.09-1.63] mmol/L was observed in controls vs T2D patients HDL—1.12 [0.96-1.32] mmol/L (P < .5). Co-occurring hypertension was present in 78% of T2D patients with systolic BP 141 [134-146] mmHg. Upon CVD risk evaluation in T2D patients—83% were at high/very high risk (41% and 42% respectively) and only 17% had moderate risk, whereas in the control group—35% had moderate risk and 65% of patients had low risk. Furthermore, none of the high and very high-risk patients had target LDL and only 23.5% of moderate risk patients were within their target LDL level. Conclusions Our findings show the prevalence of high/very high CVD risk (83%) and illustrate a constellation of modifiable CVD risk factors in patients with newly diagnosed T2D, which subjects them to an increased risk of major cardiovascular events. This emphasizes the significance of timely metabolic management alongside proper glucose control.
Institution: Belarusian State Medical University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,292
OpenAlex ID: W7213301302