Medication-related osteonecrosis of the jaw: patient management strategy (literature review)
Year: 2026
Type: article
Abstract: Background. The article presents an analysis of the literature devoted to the problem of drug-related osteonecrosis of the jaw. Materials and methods. To prepare the literature review, the authors examined, analyzed, and systematized contemporary scientific publications found in the Russian scientific electronic library eLIBRARY.RU and in PubMed, the biomedical research search engine developed by the National Center for Biotechnology Information. Results. The etiology, pathogenesis, risk factors, and key aspects of patient management at various stages of the disease are discussed. Particular attention is paid to the role of the general dentist in prevention and early diagnosis, the options for conservative treatment by an oral surgeon, and comprehensive surgical treatment performed by a maxillofacial surgeon. The necessity of a multidisciplinary approach involving oncologists and rheumatologists when deciding on modifications to systemic therapy is emphasized. Conclusions. An analysis of the literature indicates that a strategy of active prevention, early detection, and staged treatment significantly improves outcomes in patients with medicationrelated osteonecrosis of the jaw.
Institution: Penza State University
Language: English
Topic: Bone health and treatments
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7213560880