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Successful Continuation of an At-Risk Pregnancy Secondary to Severe Pulmonary Embolism

Year: 2026

Type: article

Abstract: We report the case of a 36-year-old pregnant woman who developed severe pulmonary embolism (PE) at 11 weeks of gestation. Despite prompt initiation of anticoagulation therapy, her condition deteriorated with worsening right heart dysfunction. Through meticulous management and multidisciplinary team collaboration, the pregnancy was successfully sustained, and a healthy infant was delivered safely at 37 weeks. This case highlights the clinical importance of early diagnostic imaging, careful adjustment of anticoagulation therapy, and multidisciplinary decision-making in pregnancy-associated PE. In particular, this case suggests that reduced antithrombin III activity may complicate unfractionated heparin therapy.

Source: Institutional Repositories DataBase (IRDB)

Authors: Mana Kusumoto, Tomohiro Fujisaka, Yui Wada, Akiko Ogawa, Junko Makino, Rurimi Kawamura, Atsushi Daimon, Daisuke Fujita, Yumiko Kanzaki, Masaaki Hoshiga, Hideaki Morita

Institutions: Osaka Medical and Pharmaceutical University, National Cerebral and Cardiovascular Center, Nippon Life Hospital, Osaka Medical and Pharmaceutical University Hospital, Osaka Medical and Pharmaceutical University Mishima-Minami Hospital

Language: English

Topic: Venous Thromboembolism Diagnosis and Management

Subfield: Internal Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7213857073

FWCI:

Cites: 20

Cited by:

Related to: 10