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When the Mind Leaves Early: A Bottom Up Neurobiological Account of Acute-State Dissociation

Year: 2026

Type: article

Abstract: This paper explains acute‑state dissociation through a bottom‑up neurobiological lens, showing how trauma conditioning, salience misrouting, and memory‑encoding shutdown create states where individuals appear responsive while evaluative and reflective systems are offline. It integrates research on autobiographical memory, substance‑induced impairment, and consent vulnerability to clarify how alcohol, opioids, ketamine, and stimulants amplify dissociation. The paper highlights clinical implications for assessment, risk, and interpretation, and includes a layman’s terms summary to make the mechanisms accessible to general readers.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.22981366

Author: Chad, Thomas

Institution: Ottawa University

Language: English

Topic: Psychosomatic Disorders and Their Treatments

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7214432116

FWCI:

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Related to: 10