Year: 2026
Type: article
Study design: Observational Study
Abstract: Objective: To determine the frequency and distribution of hematological abnormalities detected by automated complete blood count among blood donors at Hospital Nacional Sergio E. Bernales. Methods: A descriptive, prospective, cross-sectional study was conducted in January 2020. A total of 133 eligible donors aged 18-55 years were selected by simple random sampling. Samples were processed using a Pentra XLR hematology analyzer, and erythrocyte, leukocyte, and platelet abnormalities were summarized as frequencies and percentages. Results: Thirty-four donors (25.6%) had at least one hematological abnormality. The erythrocyte series was most frequently affected (18.8%; n=25), exclusively by erythrocytosis; leukocyte abnormalities consisted of leukocytosis (5.3%; n=7), and platelet abnormalities consisted of thrombocytopenia (1.5%; n=2). The proportion with any abnormality was 16.4% at ages 18-30, 31.9% at ages 31-43, and 32.3% at ages 44-55. Among the 34 donors with abnormalities, 79.4% were men. Conclusions: One quarter of the studied donors showed complete blood count abnormalities, predominantly erythrocytosis. These findings describe detectable abnormalities among donors previously considered eligible and support further evaluation of automated complete blood count testing in donor selection.
DOI: 10.68178/96p2yt84
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7214536289