Diagnostic Value of Pleural Fluid N-Terminal pro-Brain Natriuretic Peptide Levels in Patients with Cardiovascular Diseases
Year: 2026
Type: article
Study design: Observational Study
Abstract: Background: Pleural effusion is a prevelant complication of multiple pathologies leading to annual incidence of 3000 cases per million. The delay in diagnosing the cause of pleural effusion and treatement of the underlying cause is the major factor of mortality. Objectives: The study aims to establish the accuracy of pleural pro-Bnp in evaluating the cardiac causes of pleural effusion,. Methods: The study evaluates the level of pro-BNP measured in cardiac and non cardiac causes to identify its role in diagnosing the cause of effusion. Results: Pro-BNP levels are significantly lower in patients with pleural effusion due to hepatic hydrothorax which is 84% lower than the referral level of cardiac causes with a base value of >1714pg/ml, 94 % less in patients with tuberculosis related pleural effusion and 91% less in parapneumonic and 78% lower in effusion due to malignant causes of pleural effusion. hence showing the tests accuracy in distinguishing cardiac from non cardiac causes of pleural effusion Conclusion: Pro BNP levels can aid in distinguishing cardiac from non cardiac causes of pleural effusion. Early detection of cause with accuracy can help in early treatment and low mortality.
Institution: M. P. Shah Medical College
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7214850488