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Antibiotic Susceptibility Pattern of Uropathogens Among Catheterized and Non-catheterized Hospitalized Patients at a Tertiary Care Centre

Year: 2026
Type: article
Study design: Observational Study
Abstract: Urinary tract infections (UTIs), particularly catheter-associated UTIs (CAUTIs), are major hospital-acquired infections contributing to antimicrobial resistance.To compare uropathogens and antibiotic susceptibility patterns in catheterized and non-catheterized hospitalized patients. A hospital-based comparative study was conducted using urine samples from clinically suspected UTI patients. Isolates were identified by standard microbiological methods, and antimicrobial susceptibility testing was performed using the Kirby–Bauer method. In catheterised patients, the predominant isolates were Escherichia coli (22%), Klebsiella pneumoniae (30%), Pseudomonas aeruginosa (9%), Enterococcus spp. (22%), Candida spp. (7%), Coagulase-negative Staphylococcus (4%), Citrobacter koseri (2%), Acinetobacter baumannii (4%), Klebsiella oxytoca (1%), Enterobacter aerogenes (1%), and Proteus spp. (1%).Among non-catheterised patients, E. coli (46%) was most common, followed by K. pneumoniae (16%), Enterococcusspp. (11%), Candida spp. (12%), P. aeruginosa (8%), CoNS (3%), A. baumannii (1%), K. oxytoca (1%), and Proteus spp. (1%). Antibiotic susceptibility testing (Amikacin, Piperacillin-Tazobactam, Nitrofurantoin, Ciprofloxacin, Norfloxacin) demonstrated a higher prevalence of multidrug-resistant organisms in the catheterised group. Catheterization is associated with diverse pathogens and increased antimicrobial resistance, highlighting the need for judicious catheter use and local antibiogram-guided therapy.
Language: English
Subfield: Urology
Field: Medicine
Open Access status: hybrid
OpenAlex ID: W7214965644
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