Imidazole-type abscisic acid receptor antagonists and their use
Year: 2025
Type: other
Abstract: The present invention relates to a novel type of compounds which modulate the activity of Abscisic Acid (ABA) receptors in plants. More particularly, such novel compounds are acting as ABA antagonists, which specifically and potently block activation of clade III ABA receptors including but not only PYL1, while another subfamily of compounds has agonistic mode of action promoting activation of the receptor and the ABA signaling pathway. These compounds are, therefore, applicable in different fields of modulating target plant seed germination, modulating target plant growth, modulating tolerance to drought and abiotic stress, modulating fruit ripening, or modulating immunity of a target plant. More particularly, said compounds can be used to stimulate the germination of plant seeds, either under conditions favorable for the growth of crop plants, or unfavorable for the survival of weeds. The compounds can also be used to enhance plant growth under growing conditions where water is not a limiting factor on plant growth. The selectivity of the compounds for clade III ABA receptors will prevent unwanted effects from blocking other ABA receptor subtypes (for example in clade II and clade I groups) present in the plants of interest. The present invention also provides corresponding agrochemical compositions comprising such novel compounds.
Language: English
Subfield: Plant Science
Domain: Life Sciences
SDG: Zero hunger
Open Access status: green
OpenAlex ID: W7215160992