การพัฒนาเครื่องฉายรังสี Uv-c ในคลินิกแพทย์แผนไทยสำหรับลดการปนเปื้อนเชื้อจุลินทรีย์ในวัตถุดิบพืชสมุนไพรที่ใช้ทำยา กรณีศึกษา ขมิ้นชัน
Year: 2024
Type: article
Abstract: This study aimed to develop the UV-C projection machine in Thai traditional medicine clinic for the reduction of microbial contamination in medicinal plant raw materials and to examine the medicinal quality of medicinal plant raw materials after UV-C irradiation: a case study of Curcuma longa Linn. Thus, the knowledge of UV-C radiation was studied to design and manufacture a UV-C projection machine for reducing microbial contamination. Then, the UV-C projection machine's disinfection efficiency was examined in Curcuma longa Linn. Moreover, the fingerprint by thin layer chromatography, total phenolic contents, total flavonoid contents, and antioxidant capacities by DPPH and ABTS assay were further determined in Curcuma longa Linn. after exposure with UV-C radiation compared with non-exposure. After studying the knowledge about UV-C radiation used for the reduction of microbial contamination in raw plant materials, it could be designed and manufactured a UV-C cabinet that has characteristics as follows; in the form of an oval tunnel-type cabinet made from metal that UV-C radiation cannot penetrate the user, there is an on/off switch outside the cabinet, there is a conveyor system that allows the medicinal plant materials to move and UV-C radiation could be contacted with medicinal plant raw materials thoroughly, and there are a sufficient number of UV-C lamps and a UV dose to kill microorganisms inside the UV-C projection machine. The results of the efficiency of the UV-C projection machine found that it could reduce fungi and Clostridium spp. contamination in Curcuma longa Linn. Moreover, Curcuma longa Linn. after exposure to UV-C radiation, had no difference in the TLC fingerprint, total phenolic contents, total flavonoid contents, and antioxidant capacities when compared with non-exposure. Thus, the UV-C projection machine could be the reduction of microbial contamination without affecting the medicinal quality of Curcuma longa Linn.
Institution: Chiang Rai Rajabhat University
Language: Thai
Subfield: Biotechnology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W7215249135