Work

Intracranial foreign body granuloma caused by oxidized cellulose polymer and etherified sodium carboxymethyl cellulose: an experimental study with orictolagus cuniculus rabbits

Year: 2021

Type: article

Abstract: The purpose of this study was to analyze the brain tissue response to several haemostatic agents used during surgery, such as oxidized cellulose polymer and etherified sodium carboxymethyl cellulose on the brain of 30 Oryctolagus cuniculus rabbits. At weeks 1, 2, and 3, the specimens were euthanized. Histological examination showed etherified sodium carboxymethyl cellulose and oxidized cellulose polymer cell response. We established a significant association in foreign body granuloma. It elicited that etherified sodium carboxymethyl cellulose and oxidized cellulose polymer were linked with a substantial foreign body reaction at any point throughout the trial.

Source: International journal of health & medical sciences

DOI: 10.31295/ijhms.v4n2.1741

Authors: Fitra, Legowo, Djoko, Utomo, Budi, Suroto, Nur Setiawan, Parenrengi, Muhammad Arifin, Al-Fauzi, Asra

Institution: Universitas Airlangga

Language: English

Topic: Hemostasis and retained surgical items

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Universitas Airlangga