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Sarcoidosis as Chest Pain: an Atypical Clinical Presentation

Year: 2025
Type: article
Study design: Case Report
Abstract: A 36-year-old man reported a four-month history of left-sided chest pain accompanied by exertional dyspnea. Initial physical examination and routine laboratory tests were unremarkable. Chest X-ray showed bilateral diffuse interstitial nodular opacities with perihilar consolidations. Follow-up chest CT revealed peri-lymphatic nodularity mainly affecting the mid and upper lung zones, distributed along peri-bronchovascular bundles, subpleural surfaces, and fissures. This resulted in central upper lobe conglomerations, along with hilar and mediastinal lymphadenopathy. The next day, bronchoscopy with endobronchial ultrasound-guided transbronchial biopsy was performed. The histopathological analysis identified non-necrotizing, wellformed granulomas within dense, hyalinized, sclerotic tissue, confirming the diagnosis of sarcoidosis
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W7216824853
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