Work

Síndrome de Guillain-Barré posdengue. Reporte de caso

Year: 2026

Type: article

Abstract: Background: Guillain-Barré syndrome is an acute inflammatory demyelinating polyradiculoneuropathy of unknown origin, it appears as a post-infectious disease caused by arboviruses, with emerging evidence of dengue as a trigger for this neurological complication. Objective: To illustrate the clinical course, diagnostic and therapeutic challenges of the association between dengue and severe Guillain-Barré syndrome, likewise to contribute to the literature about the subject. Case report: We present the case of a 27-year-old patient with a history of dengue virus infection two weeks before; he had rapidly ascending weakness, tetraplegia, facial diplegia and respiratory failure. Nerve conduction studies of peripheral nerves confirmed a demyelinating polyneuropathy; cerebrospinal fluid showed albuminocytologic dissociation. He was admitted to the Intensive Care Unit, mechanical ventilation, intravenous immunoglobulin (IVIg) 0.4 g/kg/day for 5 days, multidisciplinary support. After 7 days of mechanical ventilation, successful weaning was initiated. Conclusions: This case reinforces the association between dengue and severe Guillain-Barré syndrome; it highlights the importance of early diagnosis, intensive care management, and the need for surveillance in endemic areas.

Source: Gaceta Médica Espirituana

Authors: Dueñas Valdivia, Dimitri, García Zacarías, Javier, Pérez Rodríguez, Mario, Hernández Batista, Sulema de la Caridad, López Pino, María José

Institution: Escuela Superior Politécnica de Chimborazo

Language: Spanish

Topic: Peripheral Neuropathies and Disorders

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7216985404

FWCI:

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