Year: 2022
Type: article
Study design: Observational Study
Abstract: Introduction: A significant proportion of deaths in patients with chronic ischemic cardiomyopathy are due to heart failure or sudden cardiac death (SCD) [1]. Numerous clinical trials have confirmed the benefit of implantable cardioverter-defibrillator (ICD) treatment in patients with reduced left ventricular (LV) function after an acute myocardial infarction (AMI). Objective: To measure and compare Left Ventricular Ejection Fraction (LVEF) after acute anterior wall and inferior wall myocardial Infarction and correlate LVEF with clinical findings in the patients. Methods: It was a prospective observational echocardiography based study which was carried out in the Dept. of Cardiology, Shaheed Tajuddin Ahmad Medical College Hospital, Gazipur, Bangladesh from March to October 2022. A total of 60 (sixty) patients of (anterior or inferior) Acute Myocardial infarction (AMI) were included in the study. Patients were divided in two groups on the basis of anterior myocardial wall MI (AWMI) or inferior myocardial wall MI (IWMI). Echocardiography was done on all cases and ejection fraction was calculated by applying Simpson’s Rule and patients were examined at the same time to see the presence of signs of left ventricular failure (LVF). (LVEF) was correlated with the findings of LVF in these patients. Results: Out of 30 patients of anterior wall MI, 18 (60%) were male and 12 (40%) were female. In inferior wall MI, 28 (93.3%) were male and 2 (6.7%) were female. In all 60 patients (76.7%) patients were male and (23.3%) were females. In anterior wall MI, (6.7%) were in 30 to 40 years of age, (33.3%) were in 41 to 50 years of age, (33.3) were in 51 to 60 years of age, (20.0%) were in 61 to 70 years of age, and (6.7%) were in 71 to 80 years of age. Minimum age was 39 years; maximum was 72 years, with mean of 54.57 and SD of 9.22. In patients with LVF mean ejection fraction (EF) was 37.13 with standard deviation (SD) of 8.4 %. In patients without failure the mean EF was 56.29% with SD of 3.75. In 30 patients of IWMI, mean EF was 54.93% with SD of 6.86. In 30 patients of AWMI it was 46.07% with SD of 11.72. In all 60 patients minimum EF was 30% and maximum was 60% with a mean of 50.50 with SD of 10.52. In AWMI, 53% patients had signs of left ventricular failure. In patients of IWMI, 13.3% had signs of LVF. Conclusions: AWMI causes more decrease in LVEF. LVF is more commonly associated with AWMI than IWMI. There is statistically significant difference in LVEF of patients with and without LVF.
Source: Medico Research Chronicles
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7217834157