Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Pneumonia is the 5th leading cause of death worldwide according to the World Health Organization in 2021 and the 6th leading cause of death in Thailand according to Thai health statistics in 2020. Objective: To study the mortality rate and factors associated with death from nosocomial pneumonia 28 days after treatment. Methods: Retrospective cross-sectional study collecting medical records of patients diagnosed nosocomial pneumonia from January 1st, 2021, to December 31st, 2023. The data were collection prevalence death rate and analyzed factors associated with mortality. Results: A review of medical records identified 110 patients. The majority of patients were male (70%). The mean age was 62 years. The most common pathogen was A. baumannii (multiple drug resistance) in 30.9%. The average duration of antibiotics was 9.7 days. The death rate after treatment within 28 days was 33 out of 110 (30%). The factors significantly affecting mortality include the duration of antibiotic treatment. Administering for less than 9 days (7 and 8 days) increases the likelihood of death by a factor of 2.3 ([95% CI, 1.29-4.27]; P=0.005) and intubation is performed for more than 5 days, the risk of death increases by 4.0 times ([95% CI, 1.06-15.37]; P=0.04).Conclusion: The death rate for hospitalized patients with nosocomial pneumonia after treatment is 30% within 28 days. Factors that significantly increased deaths included administering antibiotics for less than 9 days and having intubation lasting more than 5 days.
Author: Angkanavisan, Pirada
Language: English
Topic: Nosocomial Infections in ICU
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7218059145