Utilidad pronóstica de gravedad y mortalidad del Índice de inmunidad-inflamación en el paciente crítico
Year: 2026
Type: article
Study design: Observational Study
Abstract: ABSTRACT Introduction: The Systemic Inflammation-Immunity Index is a simple and cost-effective marker derived from a complete blood count, whose usefulness has been evaluated in several clinical conditions. Objective: To determine the prognostic value of the Systemic Inflammation-Immunity Index for severity and mortality in critically ill patients. Methods: A prospective, longitudinal study conducted between January and December 2024. A total of 110 patients admitted to ICU Unit 8B of “Hermanos Ameijeiras” Hospital were included. Variables analyzed included age, sex, origin, length of stay, invasive mechanical ventilation, sepsis, and discharge status. Acute Physiology and Chronic Health Evaluation II and Sequential Organ Failure Assessment scores were also calculated to estimate mortality risk. The SII was determined at 24 and 48 hours, and on day 5. The chi-square test was used to assess associations between variables, and relative risk with a 95% confidence interval was calculated to measure the strength of associations. Results: Females (54.5%), surgical cases (64.4%), and septic patients (71.4%) predominated; 56.3% required mechanical ventilation. Mortality was 39.1%. Mean the Systemic Inflammation-Immunity Index values at the three time points showed no differences between survivors and non-survivors. However, on day 5, septic patients showed significant differences between groups (p = 0.040). No correlation was found between Sequential Organ Failure Assessment or Acute Physiology and Chronic Health Evaluation II scores and the Systemic Inflammation-Immunity Index in predicting mortality at any of the evaluated time points. Conclusions: The prognostic utility of the the Systemic Inflammation-Immunity Index for severity and mortality could not be confirmed.
Source: Acta Médica
Institution: Hermanos Ameijeiras Hospital
Language: Spanish
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7218328869