การตอบสนองของระบบหัวใจและหลอดเลือดขณะออกกำลังกายแบบเกร็งค้าง ในผู้สูงอายุเบาหวานชนิดที่ 2 ร่วมกับความดันโลหิตสูง: การศึกษานำร่อง
Year: 2021
Type: article
Abstract: Background: Sympathetic nervous activity increases in either aging, diabetes type 2 or hypertension. Therefore, cardiovascular responses to static exercise may be amplified to danger level in older patients with diabetes type 2 and hypertension (DM-HT). This has not yet been studied. Objective: To examine cardiovascular responses to static exercise in elderly patients with DM-HT. Methods: Ten elderly volunteers with DM-HT age 65.6±3.84 years were tested the exercise pressor responses (EPR) with static handgrip at 30 percent of the maximum voluntary contraction and followed immediately by circulatory occlusion (post exercise with circulatory occlusion, PECO. Blood pressure (BP) and heart rate (HR) were measured at rest during exercise and PECO for 2 minutes/phase. Results:Systolic BP, mean BP and HR were significantly increased by 21.7±7.86 and 14.40 ±8.57 mmHg and 4.80±3.55 bpm during exercise respectively but not in PECO. Conclusion:The increment of cardiovascular responses to static exercise is increase in elderly with DM-HT. The responses may be contributed by central command and muscle mechanoreflex not metaboreflex stimulating the sympathetic nerve activity to cardiac mainly rather than vasomotor functions. Further study is required in larger sample size and compare with healthy elderly subjects. Keywords: Exercise pressor response, Sympathetic functions, Elderly, Diabetes mellitus type 2, Hypertension
Institution: Khon Kaen University
Language: Thai
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7219230675