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PB2623 Anticoagulant therapy as a potential modifier of tumor biology in advanced ovarian cancer

Year: 2026

Type: conference-abstract

Abstract: Activation of the haemostatic system is an integral component of tumor progression. Thrombin generation, platelet activation, and endothelial dysfunction contribute not only to venous thromboembolism (VTE) but also to tumor cell survival, angiogenesis, and metastatic dissemination. Anticoagulant therapy (ACT), traditionally used for thromboprophylaxis, may interfere with haemostasis-dependent mechanisms of carcinogenesis.

Source: Research and Practice in Thrombosis and Haemostasis

DOI: 10.1016/j.rpth.2026.105362

Authors: Alexander Vorobev, Victoria BITSADZE, Antonina Solopova, Jamilya KHIZROEVA, Natalia Makatsariya, Maria Tretyakova, Nilufar Gashimova, Alena Tatarintseva, Arina Oskolkova, Kristina Grigoreva, Dmitrii UTKIN, Grigoris Gerotziafas, Ismail Elalamy, Jean-Christophe GRIS, Alexander MAKATSARIYA

Institutions: Sechenov University, Sorbonne Université, Université de Montpellier

Language: English

Topic: Venous Thromboembolism Diagnosis and Management

Subfield: Internal Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,250

OpenAlex ID: W7220375334

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