Work

PB2451 Murine EMT-6 breast cancer is associated with increased platelet turnover and sensitization to activation

Year: 2026

Type: conference-abstract

Abstract: Platelets are key contributors to the progression of solid tumors. Tumors can alter platelet counts, induce thrombocytosis or thrombocytopenia, and modulate the functional activity of circulating platelets. However, there are limited data on changes in platelet functional activity during tumor development.

Source: Research and Practice in Thrombosis and Haemostasis

DOI: 10.1016/j.rpth.2026.105191

Authors: Artem Mishukov, Julia Korobkin, Ekaterina Iva Adamanskaia, Eugenia Shpagina, Dmitry Abramov, Mikhail Panteleev, Ekaterina Shamova, Anastasia Sveshnikova

Institutions: Center for Theoretical Problems of Physicochemical Pharmacology, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Lomonosov Moscow State University, Institute of Biophysics and Cell Engineering

Language: English

Topic: Platelet Disorders and Treatments

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,250

OpenAlex ID: W7220449285

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