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Prior hormonal contraceptive use and pre-eclampsia in Angola: a hospital-based, individually matched case–control study with incidence-density sampling

Year: 2026
Type: study-registration
Abstract: Hospital-based case–control study with individual 1:2 matching and incidence-density sampling of controls at Hospital Geral de Benguela, Angola, to estimate the association between prior hormonal contraceptive use and incident pre-eclampsia (2021 ISSHP criteria). Recruitment took place from 1 January to 30 June 2026: 165 consecutive incident cases and 330 controls randomly sampled from a daily sampling frame and matched on age (±3 years), parity group, gestational age (±2 weeks) and calendar time (±7 days). This registration deposits the ethics-approved protocol (including the statistical analysis plan), the de-identified dataset, a data dictionary, the analysis code and the STROBE checklist.
Language: English
Field: Medicine
Open Access status: green
OpenAlex ID: W7220908536
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