Chronic constipation in children: current approaches to diagnosis and treatment with osmotic laxatives. A review
Year: 2026
Type: article
Abstract: Chronic constipation in children is a multifactorial condition characterized by the interplay between the intestine and the brain. Key factors include abnormal intestinal motility, defecation reflex dysfunction, the child’s retention behavior, and alterations in the intestinal microbiota. The updated Rome V criteria (2026) underscore the importance of clinical diagnosis, early detection, and timely initiation of therapy to prevent the chronic progression of the condition and mitigate the risk of complications and relapses. The current management of children with chronic functional constipation should employ an integrated approach that encompasses family education, dietary and lifestyle modifications, a proper duration of pharmacological treatment, and ongoing follow-up. Osmotic laxatives, particularly lactulose, are used as first-line therapeutic agents due to their proven efficacy, favorable safety profile, and prebiotic properties. Implementing an algorithm based on the Rome V criteria and contemporary international clinical guidelines enhances treatment efficacy, reduces relapse rate, and improves quality of life for affected children.
Source: Pediatrics Consilium Medicum
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7221831908