Clinical Characteristics and Prognosis of Paediatric Chronic Inducible Urticaria: A Retrospective Study
Year: 2026
Type: article
Study design: Observational Study
Abstract: Background: Chronic inducible urticaria (CIndU) is rare in children, with limited data available about its clinical features and prognostic factors. Aims: This study aimed to evaluate the clinical characteristics, subtype distribution, and prognosis of paediatric CIndU in a Turkish cohort. Methods: A retrospective analysis was conducted on 60 paediatric patients diagnosed with CIndU between 2019 and 2020 at a tertiary hospital. Data were collected on demographics, subtypes, comorbidities, treatments, and outcomes. Multivariate logistic regression was used to identify factors associated with non-remission. Statistical analyses included t-tests, Mann–Whitney U tests, and Kruskal–Wallis tests ( P < 0.05). Results: Symptomatic dermographism was the most common subtype (54%), followed by cold urticaria and cholinergic urticaria (13% each). Females predominated (55%), with symptomatic dermographism significantly more common in females (71.9%, P < 0.05). Anaphylaxis occurred in three patients (5%). During follow-up (n = 51), 31.4% achieved remission, 39.2% had reduced medication needs, and 29.4% required unchanged doses. Symptomatic dermographism had the best prognosis (34.6% remission). Logistic regression showed that atopy significantly increased the likelihood of non-remission (adjusted odds ratio = 4.622, 95% confidence interval: 1.119–19.078, P = 0.035), while age, gender, and subtype were not significant ( P > 0.05). Conclusion: Paediatric CIndU is heterogeneous, with symptomatic dermographism being the most common and least severe subtype. Atopy is a significant predictor of persistent disease, contrasting with some research in the literature but supported by recent studies. Larger studies are needed to validate these findings.
Source: Indian Journal of Dermatology
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7223293147