An ultrasound model for stress urinary incontinence at six weeks postpartum
Year: 2026
Type: article
Study design: Observational Study
Abstract: Objectives: Stress urinary incontinence (SUI) after childbirth has both clinical risk factors and measurable changes in urethral support. Whether integrating these complementary features can identify affected women at six weeks postpartum remains uncertain. Methods: This retrospective, single-centre study included 454 women, divided chronologically into development (n=351) and temporal internal-validation (n=103) cohorts. LASSO selected ultrasound predictors. Ultrasound-only and combined clinical-ultrasound models were evaluated for discrimination, calibration and clinical utility. Results: SUI prevalence was 17.7 % and 26.2 % in the development and validation cohorts, respectively. LASSO retained bladder-neck mobility (BNM) and urethral funneling; the combined model additionally included age, vaginal delivery and overweight. The combined model outperformed the ultrasound-only model in development (C-statistic, 0.780 [95 % CI, 0.717-0.843] vs. 0.703 [0.634-0.771]; p=0.002). In validation, the corresponding C-statistics were 0.805 (0.716-0.894) and 0.737 (0.633-0.841), but the difference was not significant (p=0.141). The validation calibration intercept, slope and Brier score were 0.704, 1.054 and 0.161, respectively. Decision-curve analysis indicated potential net benefit at selected thresholds; continuous-predictor analysis yielded similar discrimination. Conclusions: Combining clinical and transperineal ultrasound features improved concurrent SUI identification over ultrasound features alone. External validation is required before clinical implementation.
Source: Open Medicine
Institution: University of South China
Language: English
Subfield: Urology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,373
Award: G8657025788
OpenAlex ID: W7224465213
