Prevalence and clinical manifestations of alcohol and psychoactive substance dependence syndrome in patients with post-traumatic stress disorder
Year: 2026
Type: article
Abstract: The review summarizes data on the prevalence and clinical manifestations of alcohol and psychoactive substance dependence syndrome in patients with post-traumatic stress disorder, including veterans and combatants. A narrative analysis of original studies, recent review data, and Russian clinical addiction concepts of drinking motivation and pathological craving was performed. The interpretation of the literature took into account ICD-11 diagnostic updates, including complex post-traumatic stress disorder (complex PTSD) as a distinct diagnostic category that combines the core PTSD symptoms with disturbances in self-organization: affective dysregulation, persistent negative self-concept, and interpersonal difficulties. Consideration of complex PTSD is clinically relevant for veteran and addiction-treatment samples, because this category may be associated with greater functional, social, and comorbid burden than PTSD without pronounced disturbances in self-organization. The prevalence of post-traumatic stress disorder among patients with dependence varies depending on the type of dependence, sample characteristics, and diagnostic instruments. Based on the literature, a preliminary scheme of clinically vulnerable clusters is proposed as a framework for further development of a screening model and subsequent empirical verification.
Language: English
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: diamond
OpenAlex ID: W7225100809