Carcinoma hepatocelular en pacientes con enfermedad hepática crónica de etiología etanólica
Year: 2019
Type: book-chapter
Study design: Case Report
Abstract: Background: Hepatocellular carcinoma (HCC) is a major complication of chronic liver disease, including alcohol-related cirrhosis. Early recognition and appropriate imaging are essential for diagnosis. Case presentation: We describe a 67-year-old male patient with alcohol-related chronic liver disease, portal hypertension, esophageal varices, and hypertensive gastropathy who presented with right upper quadrant abdominal pain, jaundice, weight loss, fatigue, and abdominal distension. Laboratory investigations revealed hyperbilirubinemia, elevated liver enzymes, hypoalbuminemia, and an alpha-fetoprotein concentration of 411 ng/mL. Abdominal ultrasonography demonstrated multiple hepatic nodules and features of portal hypertension. Magnetic resonance imaging confirmed established cirrhosis, multiple lesions in both hepatic lobes compatible with multifocal hepatocellular carcinoma, and portal vein thrombosis extending into the main portal trunk. Discussion: This case illustrates the diagnostic challenges of hepatocellular carcinoma in patients with advanced alcohol-related liver disease and highlights the role of contrast-enhanced imaging and alpha-fetoprotein assessment in the diagnostic evaluation. Conclusion: The case emphasizes the importance of surveillance and timely diagnostic investigation of suspicious hepatic lesions in patients with chronic liver disease.
Author: Iashchuk, Mykhailo
Institution: Hospital de Santa Luzia de Elvas
Language: Spanish
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7225259642