The effects of blunt ocular trauma in patients with inherited retinal disease: a multicenter case series
Year: 2026
Type: other
Abstract: The clinical consequences of ocular trauma in patients with inherited retinal diseases (IRDs) are poorly characterized. This study describes the characteristics, management, and outcomes of ocular trauma in IRD patients. A multicenter retrospective case series was conducted across four tertiary ophthalmic centers. Medical records were reviewed to identify patients with genetically confirmed Stargardt disease/ABCA4-associated retinopathy, X-linked retinoschisis (XLRS), PRPH2-associated retinopathy, or pseudoxanthoma elasticum (PXE) who sustained documented ocular trauma. Demographic characteristics, mechanism of injury, ocular findings, visual acuity outcomes, and follow-up data were collected. Sixteen eyes of thirteen patients were included encompassing Stargardt disease (53.8%), Pseudoxanthoma elasticum (30.8%), X-linked retinoschisis (7.7%) and PRPH2-associated retinopathy (7.7%). Mean age at trauma was 19.8 ± 10.4 years, and 92.3% were male. Mean follow-up was 30.6 ± 45.2 months. Sports-related injuries accounted for 69.2% of events, with soccer ball injuries in one-third. No patient was wearing protective eyewear. The most common trauma-related complications included commotio retinae (43.8%) and retinal hemorrhage (25.0%). Commotio retinae developed in 70% of Stargardt-related eyes. Subretinal fibrosis developed in 62.5% of all eyes (10/16). Blunt ocular trauma in IRD patients may result in significant retinal complications. Sports-related injuries were the predominant mechanism, highlighting the potential importance of protective eyewear and injury-prevention counseling in this vulnerable population.
Source: Figshare
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7225613865