Work

Conduction disorders in a patient with transthyretin amyloidosis: A case report

Year: 2026

Type: article

Abstract: Amyloid cardiomyopathy is an important and often unrecognized cause of heart failure and rhythm disturbances leading to syncope or presyncope, especially among the elderly population. For wtATTR amyloid cardiomyopathy, bradyarrhythmia is common, more often due to conduction disorders than sinus node disease itself, which may require the implantation of a permanent antibradycardia pacemaker. This paper presents 75-years old male, with the symptomatic second-degree AV block with a ventricular rate of 35/min, therefore indicating the need for the implantation of a permanent anti-bradycardia pacemaker. Pacemaker implantation can improve symptoms and prevent sudden death caused by severe bradycardia, providing an opportunity for optimal medical therapy of tachyarrhythmia, but not reducing mortality rate of cardiac amyloidosis.

Source: Srce i krvni sudovi

DOI: 10.5937/siks2601009q

Authors: Milica Šćepanović, Aleksandra Živanić, Srđan Raspopović, Aleksandar Nešković, Ivan Stanković

Institutions: Zemun Hospital, University of Belgrade

Language: English

Topic: Amyloidosis: Diagnosis, Treatment, Outcomes

Subfield: Internal Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7225629486