Year: 2026
Type: article
Study design: Case Report
Abstract: Aim. A study of a rare clinical case of duodenal neuroendocrine tumor after endoscopic full-thickness resection. Methodology. This study describes a clinical case. Results. Patient A., 45 years old. A routine esophagogastroduodenoscopy (EGD) revealed a flat, elevated tumor on the anterior wall of the duodenal bulb, up to 10 mm in size, protruding 2 mm above the mucosal surface. A biopsy was performed. Pathological examination revealed growth of the neuroendocrine tumor. An abdominal CT scan revealed no evidence of lymphadenopathy or distant metastases. A decision was made to perform endoscopic full-thickness resection (EFTR). Pathological findings: well-differentiated neuroendocrine tumor of the duodenum, grade 1, 8 mm in size, confined to the submucosa (pT1). No R0 tumor growth was detected within the resection margins. Research implications. Subepithelial tumors of the duodenum are rare neoplasms prone to malignancy, invasive growth, and metastasis. Conclusions. EFTR is a developing approach that allows for R0 resection in most cases. Currently, there is no consensus on the choice of full-thickness resection technique for duodenal tumors; only case series have been described, necessitating larger studies.
Source: MedPROSVET
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7225751241