Work

The encephalitis blind spot of neglected orthoflaviviruses circulating in Brazil and mimicry of autoimmune CNS disorders

Year: 2026

Type: article

Abstract: Diagnosis of encephalitis remains difficult in regions of arboviruses circulation. While there is evidence of neuroinvasive disease in Ilhéus, Rocio and Saint Louis encephalitis virus infections in Brazil, their role in idiopathic encephalitis remains poorly defined. Herein we delineate how limited testing, short diagnostic windows, and serologic cross-reactivity may favor misclassification of viral encephalitis as idiopathic or presumed autoimmune encephalitis.

Source: npj Viruses

DOI: 10.1038/s44298-026-00254-w

Authors: Marielena V. Saivish, Caique Alberto Dosualdo, Bruno H. G. A. Milhim, Mauricio L. Nogueira, Shannan L. Rossi, Nikos Vasilakis, Cassia F. Estofolete

Institutions: The University of Texas Medical Branch at Galveston, Faculdade de Medicina de São José do Rio Preto, Hospital de Base

Language: English

Topic: Mosquito-borne diseases and control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $2,790

OpenAlex ID: W7225815508

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