Work

Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Bladder Cancer Patients Undergoing Radical Cystectomy: A Systematic Review and Meta-Analysis

Year: 2026
Type: article
Abstract: Poster and supplementary figures presented at the Millin Meeting, Royal College of Surgeons in Ireland, Dublin, 12-13 November 2026. Systematic review and meta-analysis of the neutrophil-to-lymphocyte ratio (NLR) and survival after radical cystectomy for bladder cancer (38 studies, 12,917 patients; PROSPERO CRD420261399528). High versus low NLR was associated with worse overall survival (HR 1.77, 95% CI 1.41-2.22, 15 studies), cancer-specific survival (HR 1.73, 1.20-2.49) and recurrence-free survival (HR 1.61, 1.07-2.42). Each one-unit rise in NLR was associated with worse overall survival (HR 1.08, 1.05-1.10). The supplementary PDF contains the overall-survival forest plot, a summary table of all analyses, the characteristics of each meta-analysed study, the secondary forest plots, sensitivity analyses, the cut-off used by each study and the PRISMA flow diagram. Not peer reviewed.
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: green
OpenAlex ID: W7225820599
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