Proteins that form the nuclear pore barrier move like liquids
Year: 2026
Type: article
Abstract: Nuclear pores control molecular traffic into and out of the cell nucleus. Measurements in living cells, together with molecular-dynamics simulations, show that flexible protein chains that form the selectivity barriers of nuclear pores are highly mobile, and that a sugar modification and the carrier protein importin-β help to preserve this dynamic state. The motion of the nuclear pore protein NUP98 is regulated by a transport receptor and a sugar modification.
Source: Nature
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $12,690
OpenAlex ID: W7225820969